Katherine Heigl Reacts to Alex and Izzie's Shocking 'Grey's Anatomy' Reunion (Exclusive)

'Like, isn't that an a**hole move?' the 'Firefly Lane' star asks.

Katherine Heigl is finally reacting to that shocking Grey's Anatomy ending with Alex and Izzie.

When original cast member Justin Chambers abruptly exited the series midway through season 16, the question was raised about how he would be written out of the show.

In the March 5, 2020 episode, Grey's stunned viewers when it was revealed Alex had left Seattle to reunite with his former flame, Izzie, and they were happily raising their two young twins on a horse farm in Kansas. Alex shared in a series of heartbreaking letters to his wife, Jo, and closest friends, Meredith included, that he reconnected with Izzie after years without contact in the weeks leading up to the trial to have Meredith's medical license reinstated.

Heigl, who was promoting her upcoming Netflix drama, Firefly Lane, admitted she hasn't watched the episode in question. "I didn't see it," she told ET's Katie Krause.

After being filled in on Alex and Izzie's surprising reunion, she asked, "Wasn't he with someone?," referring to Jo.

"Listen, isn't that an a**hole move?" Heigl said.

While it appeared Heigl doesn't seem to be 100 percent on board with the way Alex's farewell involved Izzie, she didn't seem too interested in returning to the halls of Grey Sloan Memorial Hospital one more time, even amid Patrick Dempsey and T.R. Knight's returns during the current season.

"I'm super focused on this show and my passion for it," Heigl said of Firefly Lane. "I would never say never but it's not likely."

In Firefly Lane, Heigl co-stars opposite Sarah Chalke as best friends Tully and Kate, whose best friendship spans three decades. Adapted from Kristin Hannah's novel, the series charts the unlikely duo when their friendship starts at 14 years old. While Tully is brash and bold, Kate is the shy girl you never notice. But when a tragedy brings them together, they're bonded for life and inseparable best friends. Together, they experience 30 years of ups and downs -- triumphs and disappointments, heartbreak and joy and a love triangle that threatens their friendship.

For Heigl and Chalke, getting to revisit the '80s was one of the joys of being a part of Firefly Lane. 

"It was one of the many big draws for me with this project, like, 'Ooo, that's gonna be so fun.' And it was," the 42-year-old actress told ET's Rachel Smith. "I spent weeks putting together my vision board of what I thought Tully's '80s vibe was gonna be like, what her hair should be like, what her makeup should be like and it was just so fun and creative to dive back into that decade. It's wildly different than anything really."

"It was the best. It was my favorite part. We had the best time. Katie and I in the makeup trailer going, 'Wait, more hairspray, less hairspray, more earrings, blue shadow, more eyeliner!,'" added Chalke. "I have a huge soft spot for the '80s in my heart and I have a full '80s drawer over there of dress-up clothes for my kids, many of which are from the actual '80s. It was one of my favorite eras -- the music, the earrings, all of it. The shoulder pads! It was a blast and when you put on those clothes, partly because we were quite young in the '80s, you feel that. It's a whole other energy. It's like putting on this whole other body and you kinda move differently and we were just more jumpy and [more] energy."

Firefly Lane drops Wednesday, Feb. 3 on Netflix.

For more on Grey's, watch below.

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